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Drugs & Devices > Abacavir

Abacavir is an oral medication that is used to treat infections with the human immunodeficiency virus (HIV). It is available under the trade name Ziagen (GlaxoSmithKline) and in the combination formulations Trizivir (abacavir, zidovudine and lamivudine) and Kivexa/Epzicom (abacavir and lamivudine). It is in a class of drugs called reverse transcriptase inhibitors. Abacavir was approved by the Food and Drug Administration (FDA) on December 18, 1998 and is thus the fifteenth approved antiretroviral drug in the United States. Its patent will expire in the United States on 26-Dec-2009.

Adverse reactions

Abacavir can cause severe allergic reactions that may even lead to death. Stop taking abacavir and call your doctor right away if you develop a rash or at least one of the following symptoms:

  • fever;
  • excessive tiredness;
  • upset stomach, vomiting, diarrhea, or stomach pain;
  • sore throat, shortness of breath, or cough

The pharmacist will give you a Warning Card containing a list of these symptoms. If you stop taking abacavir due to an allergic reaction, never take abacavir again. If you stop taking abacavir for any other reason, do not start taking it again before consulting with your doctor.

Abacavir may cause severe liver damage and a blood condition called lactic acidosis. Tell your doctor if you drink large amounts of alcohol and if you have or have ever had liver disease. If you experience any of the following symptoms, call your doctor at once:

  • unusual bleeding or bruising;
  • loss of appetite;
  • pain in the upper right part of the stomach;
  • yellowing of the skin or eyes; or
  • upset stomach and tiredness that do not get better

Free Initial Consultation - If you or a loved one has taken Abacavir and suffered side effects, please fill out and submit the form at the right or contact us today at 1-800-780-2686 for a free case evaluation by a proficient defective drug lawyer.

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